Calculate

The ASM Withdrawal Risk Retrieval Prediction Tool calculates the cumulative risk of seizure recurrence and long-term outcomes (e.g., seizure freedom) following the withdrawal of antiaeizure medications (ASMs) in seizure-free individuals. This tool is informed by meta-analytical data to guide individualized decision-making.

Variables Used:

1. EEG Findings:
   • Options include “Normal” or “Pathological.”
   • Indicates whether EEG findings showed epileptiform activity before withdrawal.
   • Normal EEG correlates with a lower risk of recurrence compared to Pathological EEG.
2. Time Since ASM Withdrawal:
   • A slider to input the time (in months) since ASM withdrawal began.
   • Calculates evolving risks based on longitudinal data.

Outputs:

1. Risk of Recurrence:
   • Predicts the cumulative likelihood of seizure recurrence over time, helping physicians identify critical milestones for patients with varying EEG findings.
   • The tool highlights significant differences in risk between Normal and Pathological EEG groups.
2. COSY (Chance of an Occurrence of a Seizure in the next Year):
   • Indicates the likelihood of seizure occurrence in the next year for individuals, considering all patients or EEG-specific subgroups.