Calculate

LANE Score

Wang et al., 2021

DOI: 10.1016/j.eplepsyres.2021.106600

Factors and Points

• Lobar Hemorrhage:
  • Yes: 1 point
• Age:
  • <65 years: 1 point
• NIHSS Score:
  • ≥15: 2 points
• Seizures:
  • Early seizures: 2 points

Risk by LANE Score

After 2 years:

• LANE score ≥ 1: 11.9% risk
• LANE score ≥ 2: 29.2% risk
• LANE score ≥ 3: 56.4% risk
• LANE score ≥ 4: 81.8% risk
• LANE score ≥ 5: 100% risk
• LANE score = 6: No data available

Positive Predictive Value

There are no direct risk estimates for each individual point. Refer to Table 4 in the publication for Positive Predictive Value (PPV) based on the cumulative score.

Clinical Utility

The LANE score is a useful tool for identifying patients at higher risk of late seizures following intracerebral hemorrhage (ICH). It supports clinical decision-making for closer monitoring and preventive strategies.

Additional Study Information

Category	Details
Score Name	LANE Score
Population	Derivation: 602 patients, Hospital of Qingdao University (2014-2017) Validation: 521 patients, Qingdao Municipal Hospital (2015-2017)
Statistical Methods	Cox regression model
Validation Methods	Internal: Retrospective cohort (Affiliated Hospital of Qingdao University) External: Retrospective cohort (Qingdao Municipal Hospital)
Performance Metrics	c-statistic: 0.83 (derivation), 0.78 (validation) Risk scores: 10.1% (0 points) to 100% (6 points)
Generalizability	High (validated in a separate cohort)
Clinical Utility	Useful for closer monitoring and preventive strategies in patients at higher risk of late seizures.